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Transplantation Proceedings

Ipamorelin: 100-300 mcg per injection CJC-1295 (no DAC / mod GRF 1-29): 100-300 mcg per injection Frequency: 1-3 injections daily, subcutaneous, ideally on an empty stomach or 90 minutes after the last meal and before sleep Cycle length: 12-24 weeks followed by a 4-to-8-week break to avoid GH receptor downregulation Injection site: Abdomen, approximately 1-2 inches from the navel, rotating sites each injection The pre-sleep injection is prioritized because it coincides with the largest endogenous GH pulse, which occurs roughly 60-90 minutes after sleep onset and is tied to slow-wave sleep [8]

Your skin tone may gradually return to its natural baseline over time, especially with frequent sun exposure or lack of maintenance

Conversely, if you need documentation for insurance coverage or want the reassurance of extensive human trial data, PRP is the stronger choice on paper

It is not FDA-approved

DOI: 10.1016/j.jpba.2024.116374