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However, we still need better studies

The approach is not transactional

For example, after GLP-1 binding the transmembrane helices 1 (TM1) rotates clockwise when looking down the membrane helices from the extracellular face (see TM1 marked in Figure 6) and a kink is introduced in the transmembrane helix 6 (TM6), as is typical for all class B1 GPCRs

-L-

Los estudios in vitro en preparaciones de mioblastos y fibroblastos de rata L6 han investigado la cintica de activacin del receptor de Long Arginine 3-IGF-1, caracterizando la potencia biolgica mediada por el IGF-1R en relacin con el IGF-1 nativo en funcin de la secrecin de IGFBP y la unin al receptor [1]

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