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This process, which ensures an adequate supply of free CoA, is essential for the oxidation of pyruvate and helps to coordinate pyruvate dehydrogenase activity with the rate of glycolysis, thereby maintaining the bodys ability to switch between fat and carbohydrate as the main energy substrate [9]
doi: 10.3390/antiox9100914 110 HadzicT.LiL.ChengN.WalshS
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Gentler side effect profile
This does not mean a dangerous interaction will occur, but it can complicate interpretation when symptoms change
Obesity and metabolic disease can also influence the immune system 26,27,28,29 and a recent study showed that obesity converted the classical type 2 T helper (TH2)-predominant disease associated with atopic dermatitis to a more severe disease with prominent TH17 inflammation30
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