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143,144 The mutated IDH1 and IDH2 proteins are endowed with a novel ability to catalyze the reduction of -KG to generate a rare metabolite, 2-hydroxyglutarate (2-HG), while consuming NADPH

I started taking it twice a day, and after a month or so, I really started to feel a difference

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The formula is consistent across the research: protein + fiber + healthy fats, delivered without added sugar, at regular intervals throughout the day