It is studied for its ability to inhibit an enzyme called NNMT, which research links to cellular energy handling and methylation
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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
One enzyme in the urea cycle uses manganese as a cofactor
doi: 10.1016/S0140-6736(18)32260-8 38 LudvikBGiorginoFJdarEFriasJPFernndez LandLBrownKet al