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Cell (1997) 89(5):74754.10.1016/S0092-8674(00)80257-3 34 YoshimuraNMurakiSOkaHKawaguchiHNakamuraKAkuneT

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As one of the functions of the testes is to produce testosterone, which maintains male characteristics and sexual function, this needs to be replaced with life long medication. However, the site does explain that HRT is usually required when one or both testicles have been removed, and can be applied in monthly injections, gels or patches

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