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Routine consultation should occur when constipation persists beyond one week despite appropriate use of over-the-counter laxatives and lifestyle modifications

GLP-1 RA Side Effects and Considerations GLP-1 drugs are generally well-tolerated, but like all medications, they may also have specific side effects and important considerations that you should be aware of 7 : Side Effects Gastrointestinal symptoms such as nausea, vomiting, and diarrhoea are the most common

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As the CD7 + cells enter into a quiescent state, the inhibiting effect on weight regain becomes less [17]

For broader context on retatrutide's cardiovascular data across all trials, see our Cardiovascular Outcomes guide