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The authors thank Lene Wither Takla (Novo Nordisk A/S, Global Drug Discovery, Denmark) for expert technical assistance with conducting the animal studies, Heidi Solvang Nielsen (Novo Nordisk A/S, Global Drug Discovery, Denmark) for dissection of the hippocampus for RNA-seq and histology, as well as Esther Bloem and Susanne Jrgensen for assistance with protein assays (Novo Nordisk A/S, Global Research Technologies, Denmark)

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They'll consider several important factors, such as: When you last took your previous GLP-1: The timing of your last dose can affect when you should start the new medication

This redundancy may seem excessive for small-scale research, but the cost of a mid-protocol supply disruption far exceeds the modest investment of testing a backup source

doi: 10.1038/nrd4204 188 SemenzaGLRothPHFangHMWangGL

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