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Many people hold a phase longer, step back, or slow the climb when intake collapses

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Based on principles for grading of evidence for guidelines 15,16 , as well as on previously published Consensus Statements from the Pituitary Society 17 , consensus recommendations were graded as weak or strong based on the quality of the evidence (Box 1)

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This sparked internal conversation amongst the Asthetica team about safer, more sustainable alternatives like gastric sleeve surgery , so we decided to share our thoughts

Tirzepatide (Mounjaro/Zepbound) has demonstrated greater weight loss than semaglutide in clinical trials, with participants losing up to 22.5% of body weight