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Its defining trait in the research literature is selectivity: unlike older GHRPs such as GHRP-6 or GHRP-2, ipamorelin is reported to release GH without meaningfully raising cortisol, prolactin, ACTH, or aldosterone, and with only minimal appetite stimulation
However, direct studies on disc herniation models remain limited
Gastrointestinal models report protection against NSAID-induced and ethanol-induced mucosal injury
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