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At day 6, the transfection mix was prepared by mixing 72 l of selected siRNAs (1 M) with 344 l plain DMEM and 8 l DharmaFECT 1 per well (a six-well plate was used

In the 64-week OASIS 4 trial (307 adults), mean weight loss was 13.6% under the treatment-policy analysis and 16.6% among participants who stayed on treatment, versus about 2% on placebo

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