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Doseresponse effects on HbA 1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial
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Firstly, our research was primarily conducted using in vitro models, which may not fully recapitulate the complex physiological environment in vivo
PMID: 18 TorresPJSiakowskaMBanaszewskaBPawelczykLDulebaAJKelleySTet al
Slowly titrating the dose over months allows the body to clear the toxic burden without triggering a massive immune flare or severe Herxheimer reaction
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