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In each study, tirzepatide achieved its primary and key secondary endpoints for the efficacy estimand and delivered consistent safety and efficacy with sustained A1C reduction and progressive weight loss among people with type 2 diabetes: In SURPASS-1 , all three tirzepatide doses demonstrated statistically significant and clinically meaningful improvements in A1C and body weight reductions compared to placebo

Both formulations being developed in parallel

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A needle that is too short may not penetrate deep enough, leading to intradermal injection, leaking, or incomplete delivery

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