2 Factors responsible for formation of free radicals Factors contributing to the formation of free radicals include normal cellular metabolism, enzymatic reactions (such as those involving xanthine oxidase), immune system functions (like nitric oxide production by macrophages), and environmental factors (such as UV exposure and drug metabolism) [8] (Fig
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No significant differences were found in the sulfhydryl content (Fig
Glutathione is a powerful antioxidant that helps protect cells from oxidative stress, detoxifies harmful substances, and supports immune function
Notably, AMPK inhibition abolishes these benefits, confirming that -PAEs protective effects are AMPK-dependent (50)
These phytohormones have major impact on plant metabolism and play a very important role in the stimulation of plant defense response mechanisms against various stresses