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These platforms promote stem cell chondrogenic differentiation or restore chondrocyte metabolism, reconstructing cartilage architecture and advancing regenerative therapy for osteoarthritis (Table 5)

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Genes Dev 24(3):241255 Zhang J et al (2011) Activation of urokinase plasminogen activator and its receptor axis is essential for macrophage infiltration in a prostate cancer mouse model

Impairment can affect energy metabolism and nerve function