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The specific combination of folic acid and vitamins B, C, and E as well as others has improved the plasticity of nerve cell synaptic dysfunction (Kihara and Shimohama, 2004) and has restored the cognitive ability and memory in AD patients in various clinical trials (van Wijk et al., 2014)

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The Two Components: Different Mechanisms, Complementary Roles To understand why the ratio matters, the two components need to be understood separately first

N terminally MRGS(H) 6 -tagged wild type and mutant ScGrx7, PfGrx and PfGR were expressed in E

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T-4 is the parent compound