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Compared with those in normal skin fibroblast subpopulations, the expression levels of senescence- and inflammation-associated genes, including p16 (also known as CDKN2A ), SFRP4 18 , IGF1 19 , and IL1R1 were increased in keloid mesenchymal fibroblasts, whereas CCND2 , IL-6 , CXCL3 , and IL1R1 were increased in keloid pro-inflammatory fibroblasts (Fig

Genetic alterations and molecular mechanisms underlying hereditary intrahepatic cholestasis

Patsoukis, N

This matrix serves a foundation supporting the migration of epithelial cells, keratinocytes, and microvascular structures [535]

Copper is an essential trace element crucial for numerous physiological processes, many of which are vital for healthy skin

Tateishi N et al