D., Yang, B., Mller, T
Pro-inflammatory cytokines are associated with several diseases such as renal disease, 3 obesity, 4 and inflammatory bowel disease
Diabetologia 58, 21242132
In AWARD-10 [31], a 24-week, randomized, double-blind, placebo-controlled trial evaluating once-weekly dulaglutide (administered at either 1.5 or 0.75 mg) as add-on therapy to SGLT2is in a total of 424 patients with inadequately controlled T2DM, only one episode of severe hypoglycemia was reported throughout the study, in a patient treated with dulaglutide 0.75 mg, confirming the very low incidence of serious hypoglycemia with GLP-1RAs in combination with SGLT2is [31]
For policymakers, the influx of generics presents both an opportunity and a responsibility
The Unstoppable Rise of GLP-1 Agonists: Revolutionising Diabetes and Obesity Treatment Over the past two years, the pharmaceutical industry has witnessed an unprecedented surge in the development and deployment of GLP-1 receptor agonists