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2.5 Quality assessment and risk of bias In line with PRISMA guidelines, the assessment of methodological quality was conducted to evaluate the strength of evidence, recognising that methodological limitations may introduce bias

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MET dysregulation plays a role in regulating the expression levels of PD-L1 in tumors As noted earlier, the imbalance of MET in various tumors frequently leads to a significantly lower rate of response and effectiveness of ICIs, according to Chen et al