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A lack of dopamine substrates because of impaired uptake in the lesion and rapid dopamine degradation may explain the elevated SAM

When symptoms return early A subset of people on standard maintenance notice their symptoms come back well before the next scheduled dose

Analytical evaluation typically includes confirmation of compound identity, purity assessment using high-performance liquid chromatography (HPLC), and molecular mass verification via mass spectrometry

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Mild side effects noted in clinical trials have included bloating or mild cramps, gas and/ or loose stools, potential weight gain, and flushed skin