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Source: West, S et al Weight regain after cessation of medication for weight management: systematic review and meta-analysis, BMJ January, 2026 Newer incretin mimetics are the GLP-1 medications semaglutide and tirzepatide

6 ** Systematic review and meta-analysis of 37 studies of anti-obesity medications administered for at least 8 weeks and follow-up of at least 4 weeks after treatment cessation in adults with overweight or obesity

This intricate biological process may be explained by the balance between mitochondrial biogenesis and mitophagy under different physiological conditions