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Proven 20% MACE reduction in SELECT (obesity) and 26% in SUSTAIN 6 (T2D), while exenatide only achieved non-inferiority in EXSCEL

While clinical studies generally administer 50 mg of pure forskolin twice daily, most oral supplements provide 250-500 mg Coleus forskolii extract (CFE) standardized to 10% forskolin taken once or twice daily

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GRAS food ingredient note AOD-9604 was self-affirmed as Generally Recognized As Safe (GRAS) by an industry expert panel for limited food-ingredient use based on the Phase 1 and Phase 2 safety data