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Yes, in effect
Headaches or tiredness are occasionally reported because of alterations in metabolism and appetite control
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Also, high-dose B12 has been linked to acneiform eruptions in some case reports and reviews (Bahbouhi et al., 2023) as described in the PubMed record
Proceedings of the Nutrition Society 74
The Comfort-in injector can be used for a variety of medicines beyond methyl B12
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