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Indeed, tirzepatide may represent a step forward towards nephroprotection mediated by drugs acting on the incretin system [88]

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Benefits of lyophilized peptides include: Improved long-term stability Reduced degradation during storage Easier transportation Reliable laboratory preparation after reconstitution Consistent research performance Proper reconstitution should always follow validated laboratory procedures appropriate for the intended research application

Incretin-based therapies were not associated with an increased or decreased incidence of depression or self-harm compared with sulfonylureas

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Their potential repositioning as adjuncts for cancer prevention or treatment in high-risk populations like those with obesity or non-alcoholic fatty liver disease (NAFLD) needs to be investigated in translational oncology