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Development of growth hormone secretagogues

When experienced simultaneously, these effects may be more severe and prolonged, potentially leading to dehydration, electrolyte imbalances, and discontinuation of treatment

Also, it was unclear why the control patients didn't fill their GLP-1 prescriptions, leaving open the possibility of confounding

But microdosing may prevent a person from getting enough of the recommended dose for the drug to be effective, and, in many cases, side effects of GLP-1 treatment are temporary

The levels of incretins including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic hormone rise in response to a meal, and they are rapidly degraded by the enzyme dipeptidyl peptidase 4 (DPP-4) [5]