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Participants with baseline retinopathy who achieved substantial A1c reductions within the first 16 weeks of treatment faced the highest risk of progression
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The presence of these contributory factors is consistent with other research whereby patients described battles and stigmatisation from practitioners
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Additionally, mitochondrial dysfunction in AT under obese conditions can significantly increase respiration and biogenesis, promote fatty acid oxidation and alter metabolism, all of which lead to the production of excess acetyl-CoA (77, 78)
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