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however, T-cell receptor (TCR)-stimulated activation increases the expression of the Myc transcription factor, glutamine transporters (SLC38A1, SLC38A2), and glutaminolysis-related enzymes (GLS, GLUD1, GOT, GPT) to meet bioenergetic and biosynthetic requirements, resulting in T-cell proliferation 130,131,132,133

* After completing the program, the clinical results for members are particularly striking: Before program enrollment nearly 30% of members had lost less than 1 percent body weight on anti-obesity medication

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