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Abstract 13840: safety outcomes from a first-in-human study of a novel investigational monoclonal antibody, REGN5381, an agonist to the natriuretic peptide receptor 1

In general, the current evidence does not fully meet the adjusted Bradford Hill Criteria

Each subunit contains an IgG1 Fc carrier domain linked covalently to the peptide molecule

10.1007/s12041-011-0020-y 97 RamanaK

A descriptive analysis evaluated report characteristics including demographics, outcomes, and indications, and identified the top 20 concomitant medications