Copper is an essential cofactor for enzymes like lysyl oxidase (which cross-links collagen and elastin) and superoxide dismutase (SOD1), making chelation necessary for full biological efficacy

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A review of the BPC-157 literature references studies showing positive effects on ligament healing, tendon outgrowth, tendon fibroblast survival and migration, growth hormone receptor expression in tendon fibroblasts, and angiogenesis in muscle and tendon healing
The topical GHK-Cu delivers all the copper that matters for the local effect