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The changes are caused by rapid loss of subcutaneous fat and, to a variable degree, lean muscle mass during sustained caloric restriction not a direct toxic effect of semaglutide itself
For semaglutide, this would be three weeks (Canadian Journal of Anesthesia)
Manolis AA et al
It may also impact the effectiveness of birth control due to its effect on digestion
This article originally appeared on USA TODAY: The post-weight loss challenge we're not talking about enough Reporting by Sara Moniuszko, USA TODAY / USA TODAY USA TODAY Network via Reuters Connect
the formal RCT is still pending
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