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Renal epithelial cell transporters are also expressed on specific sides of the plasma membranes of these cells such that certain transporters are only found on the blood side membrane (basolateral) while others are found only on the luminal side membrane (apical)
Interestingly, in echidna GLP-1 there is less conservation of the receptor binding residues with additional changes at the N-terminal receptor binding Phe 12 (conservatively substituted to Tyr) and Asp 15 (changed to Glu) residues
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Daily Value (DV) not established
Confirmation the patient is not receiving PBS-subsidised SGLT2-i, DPP-4 i, or another GLP-1 RA.
