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In Study 6 (NCT#03811574), WEGOVY injection was escalated to 1.7 mg or 2.4 mg subcutaneous weekly dosages or placebo over 12 to 16 weeks followed by 52 weeks on either maintenance dose

This form is well-absorbed and more stable throughout the digestive tract than other forms on the market

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However, its overall effects on mortality, cardiovascular (CV) and kidney outcomes have not been comprehensively synthesized

For split dosing, where total exposure stays the same, the implication is that efficacy should be essentially preserved