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Davies MJ, Aroda VR, Collins BS et al (2022) Management of hyperglycaemia in type 2 diabetes, 2022
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The amount and rate at which patients lose weight may depend on how healthy their overall diet and lifestyles are, as well as other factors such as age or metabolism
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[2] The head-to-head ACHIEVE-3 trial, published in The Lancet in February 2026, compared orforglipron 36 mg to oral semaglutide 14 mg in 1,698 patients with type 2 diabetes over 52 weeks