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This enzyme is overactive in individuals with excess abdominal fat and metabolic dysfunction
57,59 Exenatide, a synthetic peptide with 50% sequence homology to GLP-1, is resistant to dipeptidyl peptidase-4-mediated degradation 54 and was the first GLP-1RAs approved by the US Food and Drug Administration (FDA) for T2DM treatment in 2005
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Hanna, S., Sethiadi, J., Ali, Q., & Sinha, S
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