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Individuals who are pregnant, planning pregnancy or breastfeeding should discuss treatment options with a qualified healthcare professional before starting GLP-1 therapy

How should healthcare systems handle limited supply

Eli Lilly has warned the public about potential safety risks of taking compounded versions of its blockbuster weight-loss and diabetes drug tirzepatide

Mechanism : at optimal dose (1-2 g/day), muscle L-carnitine concentrations increase sufficiently to saturate the "carnitine shuttle," maximizing the flux of fatty acids to the mitochondria

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4F) and non-mitochondrial OCR (Fig