Highlights GDC temporarily decreases TEER in Caco-2/HT29-MTX monolayers, without cytotoxicity GDC decreases OCLN fluorescence intensity and increases lactulose paracellular transport GDC increases acidic mucins production and decreases intracellular cAMP GDC treated monolayers are biocompatible with Infant Formula digesta 1 Introduction The infant gut barrier has a higher paracellular permeability during early development ( There are ethical and logistical challenges of conducting clinical trials in early infancy to understand the gut barrier
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Dallapiccola B et al
117 Overall, miRNAs can have therapeutic applications in preventing airway inflammation by modulating FOXC1 and other signaling molecules, such as PI3K, AKT, NF-B, cyclin D1, and TGF-1