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Two of the most commonly referenced forms are: GHK-Cu (Copper Tripeptide-1) AHK-Cu (Copper Tripeptide-3) While both belong to the copper peptide family, they are used differently in cosmetic formulation depending on whether the goal is skin-focused or scalp- and hair-focused performance
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Unlike other organisms, some plants synthesize glutathione analogs in which -alanine, serine, or glutamate replaces glycine in the tripeptide (Figure 4A)
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Joint Pain/Stiffness: Some users report joint pain or stiffness (arthralgia), particularly when using higher doses
S.DugarB.et al (2011)
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