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When GLP-1 receptor agonists chronically stimulate these receptors, the C-cells proliferate

10.1002/iub.1182 IUBMB Life 29 LytriviM.Anne-LaureC.PoitoutV.CnopM

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Glucagon-like peptide-1 (GLP-1) receptor agonists show promise for treating fatty liver disease, particularly in patients with type 2 diabetes or obesity

While the studies supporting these benefits were not initially focused on kidney health and included patients with low kidney risk, they suggest a link between GLP-1 RAs treatment and kidney protection, especially for type 2 diabetes patients with CKD 18