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A phase 3 trial of simufilam (NCT05575076) was started in November 2022 to assess the long-term safety and tolerability of simufilam in participants with mild-to-moderate AD
Some are celebrating improved metabolic markers
It is not approved for human use Is GLP-3 safe for human consumption
Tirzepatide is a dual GLP-1 (glucagon-like peptide-1) and GIP (gastric inhibitory polypeptide) receptor agonist, which means it targets two pathways in the body to regulate blood sugar and hunger
Similar to our primary analysis, we calculated 3 different comorbidity scores: the VHA frailty index 60 , the weighted CCI 61,62 ,and cardiovascular risk as calculated by DAgostino method 63
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