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Clinical Update 8/19/2015 Cocoa Increases Blood Flow to Brain A small study found that drinking a cocoa drink high in flavanols significantly increased blood flow to the brain, which, the researchers propose, might have potential cognitive benefits

Metabolic impairment The brain is an organ that requires a lot of glucose to produce energy, with almost 70 percent of the energy used by neurons

When pharmacotherapy is needed, alternatives include phentermine-topiramate (Qsymia), which requires monitoring for psychiatric effects and is contraindicated in pregnancy

doi: 10.3389/fonc.2024.1392375 Received 27 February 2024 Accepted 02 April 2024 Published 18 April 2024 Volume 14 - 2024 Edited by Karuna Rasineni, University of Nebraska Medical Center, United States Reviewed by Luigi Losco, University of Salerno, Italy Asher Rajkumar Rajan, University of Nebraska Medical Center, United States Updates Copyright 2024 Crowley, Brown, Gallagher and Dayan

doi: 10.3389/fendo.2020.586529 140 BelkaidYHandTW

Lower-dose therapy did not fully match continued high-dose therapy, but it preserved a large amount of the benefit