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This is different from freezing AFTER reconstitution (which is harmful)

Given that BSO possesses non-specific pharmacological activities, the authors concluded that this effect was independent of the inhibition of GSH biosynthesis 15

doi: 10.1186/s11658-022-00350-8 167 GaoCWangBChenQWangMFeiXZhaoN

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Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B 12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting. Clinical practice guidelines British Columbia Medical Services Commission (MSC)

If you order a multi-pack, the policy still applies: you can keep the first bottle, but you'll need to return any remaining unopened bottles (at your own expense) to receive a refund