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It accounts for less than 1% of COPD cases but results in onset of COPD at an earlier age (20-50 years)

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Given the coupling between copper and energy status (e.g copper is a cofactor at Complex IV of the ETC) and how intensely metabolically active neurons are, it seems like short-term IP GHK-cu in the brain is acting analogously to the copper ionophore elesclomol in Tregs

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Some prescribers used a schedule like this: Weeks 1 to 4: 3 mg daily Weeks 5 to 8: 4 mg daily Weeks 9 and beyond: 5 mg daily (if tolerated and additional effect desired) Others kept patients at the starting dose longer if they were experiencing adequate appetite suppression

Potential Heart Attack Risk: Although uncommon, reports suggest the need for vigilance in patients with pre-existing heart conditions