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Since levothyroxine requires an acidic gastric environment for optimal dissolution and absorption, and its absorption can be affected by the rate of gastric emptying, patients may experience variations in thyroid hormone levels when starting semaglutide therapy

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One of the hallmark pathophysiological features of TBI is the disruption of the BBB [84, 115,116,117,118,119]

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A slightly higher MTX dosage was associated with a greater incidence of intolerance, probably due to an increased drug concentration in the blood, triggering the CTZ