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Tirzepatide therapy begins with a low starting dose to minimize gastrointestinal side effects and allow the body to adjust to the medication
Tirzepatide has been called a "twincretin" because it mimics two incretin hormones simultaneously
Injection procedures are more complicated with once-weekly medications
The effects of canagliflozin in type 2 diabetes in subgroups defined by population-specific body mass index: insights from the CANVAS program and CREDENCE trial
They share the same receptor target and produce the same downstream effects: appetite suppression via hypothalamic signaling, delayed gastric emptying, enhanced glucose-dependent insulin secretion, and suppressed inappropriate glucagon release
(August 2015)
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