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Safety Monitoring and When to Contact Your Healthcare Team While taking tirzepatide and birth control together, monitor for signs of breakthrough bleeding or spotting, which may occur if pill absorption is compromised during early dose escalation

Journal of Clinical Endocrinology & Metabolism, 91(3), 799805

This concern is particularly relevant for patients with stricturing CD, in whom up to 50% develop fibrostenotic complications within 10 years of diagnosis (74)

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