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Research into these mechanisms is still evolving, and microdose-level effects have not been specifically studied in clinical trials, but the biological rationale is sound: activating two complementary hormonal pathways at low levels may produce a broader metabolic nudge than activating one pathway alone

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(2017), carnitine conjugated nanoparticles were reported to undergo caveolin-mediated, clathrin-mediated endocytosis and micropinocytosis in Caco2 cells (86)

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