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Theres a rationale behind localized injection: some practitioners use it near a specific treatment area on the theory that proximity might concentrate effects locally

Nishida, K

Li Qian, Wenjun Wang, Yan Zhou, Jianxin Ma

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The SCN may synchronize the growth hormone (GH) secretion rhythm with the dimming cycle through somatostatin neurons, and the change of the clock system may be related to the pulsatile release of GH

This process, also known as cell turnover, is aided by exfoliation