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For example, lymphoid-specific helicase (LSH), a DNA methylation modifier, can activate lipid metabolism-associated genes to inhibit ferroptosis by interacting with WDR76 (Jiang et al., 2017), and together with another W40 protein DCAF8, they function as a crucial nexus in epigenetic regulation of ferroptosis, controlling LSH degradation by adapted oxidative damage sensing through DNA hydroxymethylation (Huang et al., 2020)
Morgante G, Darino I, Span A, Luisi S, Luddi A, Piomboni P, Governini L, De Leo
Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials
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