The potential downsides aren't just about losing a bit of money on a bad product
Proton pump inhibitors (PPIs) and H2-receptor antagonists, used for acid reflux, reduce stomach acid production, which can impair dietary B12 absorption, though this does not directly affect injections
Since a healthy digestive system contributes to your livers ability to generate good levels of glutathione for your cells, it makes sense to optimize your gut health
Improves Insulin Sensitivity and Metabolic Health Glutathione plays a key role in balancing blood sugar levels and improving how your body uses insulin
Standard GI research endpoints include: macroscopic damage scoring (CDAI-equivalent scales in IBD models), histological assessment (H&E staining, villus/crypt morphometry), tight junction protein expression (Western blot, immunofluorescence), permeability assays (FITC-dextran, Ussing chambers), and inflammatory cytokine panels
NEJM , 359(7):715-721.