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Post hoc analysis by CV risk Pooled key baseline characteristics, CV risk factors, and manifestation of CVD at baseline for the two CV subgroups [subjects with prior MI or stroke vs no prior MI or stroke and subjects with established CVD vs risk factors only (including CKD)] are shown in Table 1C

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3.5 Ferroptosis-induced disruption of the bloodbrain barrier in Alzheimers disease The bloodbrain barrier (BBB) is a critical structural interface that maintains central nervous system (CNS) homeostasis by restricting the translocation of blood-derived substances, inflammatory mediators, iron ions, and immune cells into the brain parenchyma through its tight junction architecture

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